Director, Portfolio Governance

The Director, Portfolio Governance is a strategic leadership role accountable for designing, enabling, and continuously improving the Development governance framework that drives high-quality, timely decision-making across the development portfolio. This role embeds decision excellence, clarity of decision rights, and disciplined execution across the governance forums.
This leader ensures decisions are made at the right level, with the right information, at the right time—enabling portfolio tradeoff decisions, reducing cycle time, and improving decision quality and durability.

This role is a hands-on contributor and people manager responsible to build relationships at all levels of the organization in order to solicit and action stakeholder input regarding the governance framework. This role will navigate the fast-paced and agile environment of Regeneron in a collaborative and innovative manner.

***Please note this role is an onsite opportunity and is not eligible remote.

A typical day in this role looks like:

• Own and continuously evolve the governance framework to enable effective, scalable decision-making across the portfolio.
• Establish and enforce decision quality and readiness standards, including clear articulation of options, trade-offs, risks, and recommendations.
• Where required, facilitate governance forums to ensure structured, decision-focused discussions and clear, actionable outcomes.
• Define and manage governance performance metrics (e.g., decision cycle time, right-first-time decisions, deferrals, forum utilization) to assess effectiveness.
• Translate governance metrics and feedback into actionable insights, driving a closed-loop continuous improvement model.
• Synthesize governance outputs into portfolio-level insights, identifying cross-program risks, recurring issues, and systemic bottlenecks.
• Establish and maintain centralized decision documentation and knowledge management practices to ensure transparency and traceability.
• Oversee governance intake, prioritization, and scheduling to ensure alignment to strategic importance, while advancing efficient, scalable processes and leveraging technology to streamline execution.
• Drive cross-forum integration to streamline escalation pathways, eliminate duplication, and improve decision flow.
• Partner closely with senior leaders, governance chairs, and stakeholders to align priorities and reinforce governance expectations.
• Implement governance quality and experience measurement, incorporating multi-directional feedback from teams, executives, and chairs to improve effectiveness.
• Coach and develop team members ensuring that the organizational strategy delivers the skills, capabilities and processes that enable portfolio delivery are present in his/her team

This role may be for you if you have:

• Deep understanding of drug development lifecycle and portfolio management.
• Proven experience designing governance frameworks, operating models, or decision-making processes.
• Strong analytical skills with ability to translate data into insights and actions.
• Experience with process improvement methodologies (Lean, Six Sigma) preferred.
• Exceptional executive communication and facilitation skills.
• Demonstrated ability to influence senior leadership and drive change in matrixed environments.
• Strong stakeholder management and cross-functional leadership capabilities.
• Demonstrate experience leading and developing high-performance teams, including direct people management.
• Experience leveraging technology and digital solutions to enable scalable processes, improve efficiency and enhance decision-making (e.g. dashboards, workflow tools, analytics platforms).
• Ability to travel (<10%).

In order to be considered qualified for the this role a minimum of a Bachelor's degree and Minimum 12+ years of experience in biotechnology, pharmaceutical development, or consulting.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit . For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)