Scientist - Biological Analytical Development

States considered:

Zoetis is a global animal health company dedicated to supporting customers and their businesses. Building on 60 years of experience, we deliver quality medicines, biopharmaceuticals, and vaccines, complemented by diagnostic products and genetic tests and supported by a range of services. We are working every day to better understand and address the real-world challenges faced by those who raise and care for animals in ways they find truly relevant.

Zoetis discovers, develops, and manufactures a diverse portfolio of animal health medicines, biopharmaceuticals, and vaccines designed to meet the real-world needs of veterinarians and the livestock farmers and companion animal owners they support. Zoetis has the first monoclonal antibody therapy for treating atopic dermatitis in dogs. We are currently seeking to fill a new position to support our growing biopharmaceutical portfolio.

Zoetis Veterinary Medicine Research and Development, Biological Analytical Sciences, in Kalamazoo, MI, is seeking an Analytical Scientist at the Scientist level. The successful candidate will possess a strong foundation in protein chemistry and characterization of biological molecules. The candidate must be highly motivated to contribute to the characterization and novel method development for biological products as well as robust understanding of the techniques and assays used for protein characterization. Agility in data analytics is highly preferred. Self-motivation, excellent problem-solving skills and communication, and an ability to work independently and within a group are essential to this role.

Responsibilities include, but are not limited to, the following:

* Characterization of biological molecules, identify degradation pathways, and define critical quality attributes. Contribute to analytical method development, qualification, validation, and transfer activities. Primary techniques are capillary gel electrophoresis (CGE), High performance liquid chromatography (HPLC), spectrophotometric, microplate assays and intact mass spec.

* Maintain familiarity with scientific literature and apply new knowledge appropriately to projects.

* Convey complex and nuanced concepts to interdisciplinary teams through oral and written presentations, and reports.

* Work in collaboration with other scientists to advance the development of state-of-the-art techniques to characterize biopharmaceutical products, assays, and tools. Develop high- throughput and/or automated methodologies for sample preparation.

* Develop creative solutions to moderately complex problems.

* Document and communicate results in electronic laboratory notebooks, technical reports, and oral presentations.

Minimum Qualifications:

* BS or MS in Chemistry, Biochemistry, Biology, or other related discipline, with extensive industry experience, preferably in the animal health biopharmaceutical industry.

* Motivated self-starter with excellent communication (oral and written), interpersonal, and organizational skills.

* Extensive experience in separation technologies including multiple modes for HPLC and capillary electrophoresis (e.g., SEC, RP-HPLC, IEX, icIEF, CE-SDS) for the analysis of complex proteins.

* Experience in developing, and validating biopharmaceutical analytical methods, including liquid chromatography (UHPLC), electrophoretic separations, and glycoprotein analysis.

* Candidate demonstrates a breadth of diverse experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

* Understanding of protein structure, post-translational modifications (including glycans) and potential sequence liabilities (e.g oxidation, deamidation, and clipping)

* Prepare comprehensive analytical reports and presentations, conveying findings to both technical and non-technical stakeholders.

* Strong problem-solving skills and a proactive attitude toward process improvement

Preferred Qualifications:

* Proficiency in Empower and Chemstation chromatographic software.

* Ability to recognize anomalous and inconsistent results and interpret outcomes.

* Familiarity with biopharmaceutical manufacturing processes, including cell culture, purification, and formulation.

* Experience and understanding of intact mass spec analysis of biological products using LC-MS

* Experience in SDS-PAGE gel digestion for LC-MS protein identification

* Strong understanding of Endotoxin detection assays

* Skills and experience in experimental design, technical problem solving and continuous improvement; deepens technical knowledge through exposure and continuous learning.

* Knowledge of regulatory guidelines used for biopharmaceuticals such as ICH, USP, EMA or FDA.

About Zoetis


At Zoetis , our purpose is to nurture the world and humankind by advancing care for animals. As a Fortune 500 company and the world leader in animal health, we discover, develop, manufacture and commercialize vaccines, medicines, diagnostics and other technologies for companion animals and livestock. We know our people drive our success. Our award-winning culture, built around our Core Beliefs, focuses on our colleagues' careers, connection and support. We offer competitive healthcare and retirement savings benefits, along with an array of benefits, policies and programs to support employee well-being in every sense, from health and financial wellness to family and lifestyle resources.

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